NEET PG & INI-CET - Para-Clinical Sciences (Pathology, Pharmacology & Microbiology)

Virology, Immunology & Parasitology question bank (Medical Microbiology & Parasitology)

Practice 5,061 free NEET PG & INI-CET - Para-Clinical Sciences (Pathology, Pharmacology & Microbiology) Medical Microbiology & Parasitology - Virology, Immunology & Parasitology questions with answers and step-by-step solutions.

Q1.
[Pathology & Genetics] Case Assessment #1: A 62-year-old male with chronic myeloid leukemia (CML) carries the t(9;22)(q34;q11) translocation. What is the molecular target?

(A)
FLT3 internal tandem duplication accelerating blast proliferation
(B)
BCR-ABL fusion oncoprotein with constitutive tyrosine kinase activity
(C)
PML-RARA fusion inhibiting granulocyte differentiation
(D)
JAK2 V617F point mutation conferring cytokine hypersensitivity
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Q2.
[Medical Pharmacology] Case Assessment #4: A 55-year-old hypertensive patient with type 2 diabetes and microalbuminuria requires therapy. What is the first-line agent?

(A)
ACE inhibitor or Angiotensin Receptor Blocker (ARB) due to efferent arteriolar vasodilation
(B)
Dihydropyridine CCB due to selective constriction of afferent arteriole
(C)
Thiazide diuretic due to inhibition of Na-Cl cotransporter in proximal tubule
(D)
Beta-blocker due to negative inotropic and chronotropic suppression
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