A cell suspension of actively respiring mitochondria is treated with either chemical X (experiment 1) or chemical Y (experiment 2), or left untreated (experiment 3). Chemical X selectively inhibits electron transport from Complex I to ubiquinone, while chemical Y selectively inhibits electron transport from Complex III to cytochrome C. Which one of the following options represents the correct order of relative number of ATP synthesised in mitochondria?
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Q1.
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Q2.
Consider a mitochondrion in which the $F_0$ subunit of ATP synthase is mutated, such that it can still passively conduct protons but is mechanically uncoupled from the $F_1$ subunit. If such a mitochondrion is provided with succinate, ADP, and $P_i$ in aerobic conditions, the correct outcome based on chemiosmotic theory is:
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